First off it's not "unbiased" if it's written by someone that sells tunes or equipment, or advertises for those companies. Yes when you add more parts to an engine, you add more points of failure, no one's arguing that. Fact is I've seen stock 6.0's with full EGR last just as long as deleted ones, I pulled one apart with 360,000 miles on it and all the crosshatching still looked perfect. The introduction of DEF allows for engines to require significantly less EGR than the older versions by counteracting NOx chemically vs by reducing cylinder temps with EGR. These engines shut the EGR off entirely at high load, which is when you're producing the most soot, and uses only SCR to manage NOx... when you're just cruising down the highway you're not producing much soot at all, and thus it doesn't matter if you recirculate exhaust. Yes more soot will make its way in, but significantly less of it than that of the older emission systems. These engines also have an air oil separator on the crank case which will help to reduce oil getting into the intake which reduces the issue further. In reality i've seen gasoline DI engines plug up just as bad as diesel, often sooner. This engine should last a long time before any major work is needed, deleted or not. Yes your DPF will eventually need to be serviced or replaced, but i don't see a point in deleting until then, which would be around 200,000 miles, and most people ditch their trucks long before then.
And to your emissions point, there's a big difference between creating slightly more CO2 emissions from burning a little extra fuel, vs releasing NOx emissions that are 25 times higher, and large amounts of soot. Firstly a component of NOx, N2O, is 298 times more potent of a GHG than CO2, and thus reducing that has a significant impact on climate. Other NOx components are the main contributors to smog and we all know that isn't good for human health. Soot, specifically of the PM2.5 variety, has the ability to penetrate deep into your lungs where it can sit, and cause cancer and other lung diseases, so I don't know why anyone's a fan of that. Soot also settles out everywhere, even up in the arctic blackening the surface, which absorbs more radiation, increasing the surface temperature, further melting snow and ice, and leading to a reduced albedo effect solidifying the positive feedback loop of climate change.. So there are a lot of reasons to reduce these "emissions" and not worry about the little extra CO2 which is essentially harmless in comparison. Lastly Urea isn't toxic, it readily breaks down in the environment if released.. it's pee. The chemical reaction between this and components in NOx leads to Nitrogen and water... nitrogen is already 80% of what you breathe, so out the pipe it's essentially harmless. Yes plastic bottles suck, use the truck stop if you don't know how to recycle.
So consider these facts before you delete. You're doing yourself and everyone around a favour by not deleting your truck.